PMAP Toolkit

Tool Name Description
Active Site Recognition Tool This tool finds active sites of serine, cysteine, aspartic, metallo, and glutamic proteases within the 3D structure.
Prediction of Disorder in Proteins This tool arrives at a consensus prediction of intrinsically disordered regions in proteins using results from five different algorithms. The tool requires the input of a FASTA file(s).
Substrate Recognition Profiling This is a tool that uses information from substrate profiling studies (e.g., phage display or peptide libraries) to arrive at a consensus substrate recognition motif. This motif can then be projected across individual proteins, or even the entire proteome, to predict cut sites.
Proteolytic Dissociation Tool This tool determines the likelihood that a protein will dissociate into two polypeptides following proteolytic cleavage at a specific site.