MMP15
Functional Attributes in Pathways
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Substrates : 17 entries in CutDB for M10.015
Ext
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Substrate Specificity for MMP15
-
Inhibitors -- Under development
-
Pathways -- Under development
Recent News and Literature
- Imatinib inhibits colorectal cancer...Int J Cancer. 2007 Dec 15;121(12):2808-14.
- Gonadotropin-releasing hormone analogues alter...Anticancer Res. 2006 Nov-Dec;26(6B):4615-21.
- Profiling markers of prognosis...Clin Cancer Res 2006 Feb 15;12(4): p1184-91
- Individual Timp deficiencies differentially...J Biol Chem. 2006 Apr 14;281(15):10337-46. Epub 2006 Feb 9.
- PACE4 expression in mouse...Cancer Res 2005 Aug 15;65(16): p7310-9
- Upregulated MT1-MMP/TIMP-2 axis in the TSU-Pr1-B1/B2...Clin Exp Metastasis 2005;22(2): p115-25
- The chemokine stromal cell...Carcinogenesis 2005 Dec;26(12): p2069-77
- Expression of matrix metalloproteinases...Oncol Rep 2005 Jun;13(6): p1043-8
- Expression of MMPs and TIMPs...Anticancer Res. 2004 Nov-Dec;24(6):4025-30.
- Matrix metalloproteinase/tissue inhibitors of matrix...Clin Cancer Res 2004 Dec 15;10(24): p8229-34
- Correlation of tumor- and stromal-derived...Gynecol Oncol 2004 Dec;95(3): p437-48
- Upregulation of matrix metalloproteinases...Int J Cancer 2005 Apr 20;114(4): p544-54
- Differences between scirrhous and non-scirrhous...Clin Exp Metastasis 2004;21(3): p223-33
- Expression of matrix metalloproteinases...Clin Cancer Res. 2004 Jul 15;10(14):4746-53.
- A study on angiogenesis-related...J Exp Clin Cancer Res 2003 Sep;22(3): p461-70
- Proteases in brain tumour...Acta Neurochir (Wien 2003 Sep;145(9): p825-38
- Endothelial tubulogenesis within fibrin...J Cell Sci 2002 Sep 1;115(Pt 17): p3427-38
- Malignant conversion of non-tumorigenic...Carcinogenesis 2002 Apr;23(4): p565-72
- Immunohistochemical study of membrane...J Dermatol Sci 2002 Feb;28(2): p119-25
- Expression of membrane-type 1, 2, and 3 matrix...Am J Clin Pathol 2001 Apr;115(4): p517-24
Structural Features
MGSDPSAPGRPGWTGSLLGDREEAARPRLLPLLLVLLGCLGLGVAAEDAEVHAENWLRLYGYLPQPSRHMSTMRSAQILA
SALAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVRVKANLRRRRKRYALTGRKWNNHHLTFSIQNYTEKLGWYHS
MEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKEADIMVLFASGFHGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEP
WTFSSTDLHGNNLFLVAVHELGHALGLEHSSNPNAIMAPFYQWKDVDNFKLPEDDLRGIQQLYGTPDGQPQPTQPLPTVT
PRRPGRPDHRPPRPPQPPPPGGKPERPPKPGPPVQPRATERPDQYGPNICDGDFDTVAMLRGEMFVFKGRWFWRVRHNRV
LDNYPMPIGHFWRGLPGDISAAYERQDGRFVFFKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHTFF
FQEDRYWRFNEETQRGDPGYPKPISVWQGIPASPKGAFLSNDAAYTYFYKGTKYWKFDNERLRMEPGYPKSILRDFMGCQ
EHVEPGPRWPDVARPPFNPHGGAEPGADSAEGDVGDGDGDFGAGVNKDGGSRVVVQMEEVARTVNVVMVLVPLLLLLCVL
GLTYALVQMQRKGAPRVLLYCKRSLQEWV
Cross annotation in other databases
MMP15 in:
Gene Cards
- Diseases
- Expression
- SNP
- Drugs
Other Links
- Human Protein Atlas
- iHOP
- GNF Sym Atlas
- NCBI Homologs
- OMIM
- MEROPS
Functional Attributes in Pathways
- Substrates : 17 entries in CutDB for M10.015 Ext
- Substrate Specificity for MMP15
- Inhibitors -- Under development
- Pathways -- Under development
Recent News and Literature
- Imatinib inhibits colorectal cancer...Int J Cancer. 2007 Dec 15;121(12):2808-14.
- Gonadotropin-releasing hormone analogues alter...Anticancer Res. 2006 Nov-Dec;26(6B):4615-21.
- Profiling markers of prognosis...Clin Cancer Res 2006 Feb 15;12(4): p1184-91
- Individual Timp deficiencies differentially...J Biol Chem. 2006 Apr 14;281(15):10337-46. Epub 2006 Feb 9.
- PACE4 expression in mouse...Cancer Res 2005 Aug 15;65(16): p7310-9
- Upregulated MT1-MMP/TIMP-2 axis in the TSU-Pr1-B1/B2...Clin Exp Metastasis 2005;22(2): p115-25
- The chemokine stromal cell...Carcinogenesis 2005 Dec;26(12): p2069-77
- Expression of matrix metalloproteinases...Oncol Rep 2005 Jun;13(6): p1043-8
- Expression of MMPs and TIMPs...Anticancer Res. 2004 Nov-Dec;24(6):4025-30.
- Matrix metalloproteinase/tissue inhibitors of matrix...Clin Cancer Res 2004 Dec 15;10(24): p8229-34
- Correlation of tumor- and stromal-derived...Gynecol Oncol 2004 Dec;95(3): p437-48
- Upregulation of matrix metalloproteinases...Int J Cancer 2005 Apr 20;114(4): p544-54
- Differences between scirrhous and non-scirrhous...Clin Exp Metastasis 2004;21(3): p223-33
- Expression of matrix metalloproteinases...Clin Cancer Res. 2004 Jul 15;10(14):4746-53.
- A study on angiogenesis-related...J Exp Clin Cancer Res 2003 Sep;22(3): p461-70
- Proteases in brain tumour...Acta Neurochir (Wien 2003 Sep;145(9): p825-38
- Endothelial tubulogenesis within fibrin...J Cell Sci 2002 Sep 1;115(Pt 17): p3427-38
- Malignant conversion of non-tumorigenic...Carcinogenesis 2002 Apr;23(4): p565-72
- Immunohistochemical study of membrane...J Dermatol Sci 2002 Feb;28(2): p119-25
- Expression of membrane-type 1, 2, and 3 matrix...Am J Clin Pathol 2001 Apr;115(4): p517-24
Structural Features
MGSDPSAPGRPGWTGSLLGDREEAARPRLLPLLLVLLGCLGLGVAAEDAEVHAENWLRLYGYLPQPSRHMSTMRSAQILA
SALAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVRVKANLRRRRKRYALTGRKWNNHHLTFSIQNYTEKLGWYHS
MEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKEADIMVLFASGFHGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEP
WTFSSTDLHGNNLFLVAVHELGHALGLEHSSNPNAIMAPFYQWKDVDNFKLPEDDLRGIQQLYGTPDGQPQPTQPLPTVT
PRRPGRPDHRPPRPPQPPPPGGKPERPPKPGPPVQPRATERPDQYGPNICDGDFDTVAMLRGEMFVFKGRWFWRVRHNRV
LDNYPMPIGHFWRGLPGDISAAYERQDGRFVFFKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHTFF
FQEDRYWRFNEETQRGDPGYPKPISVWQGIPASPKGAFLSNDAAYTYFYKGTKYWKFDNERLRMEPGYPKSILRDFMGCQ
EHVEPGPRWPDVARPPFNPHGGAEPGADSAEGDVGDGDGDFGAGVNKDGGSRVVVQMEEVARTVNVVMVLVPLLLLLCVL
GLTYALVQMQRKGAPRVLLYCKRSLQEWV
Cross annotation in other databases
MMP15 in:
- Gene Cards
- Diseases
- Expression
- SNP
- Drugs
- Other Links
- Human Protein Atlas
- iHOP
- GNF Sym Atlas
- NCBI Homologs
- OMIM
- MEROPS

