Functional Attributes in Pathways

• Substrates : 300 entries in CutDB for C02.002 Ext
  • aggrecan
  • A-kinase anchor protein 11
  • adherin-3 precursor
  • aggrecan
  • Alpha-soluble NSF attachment protein
  • alpha-spectrin 2
  • amphiphysin isoform 1
  • androgen receptor isoform 1
  • AP-2 complex subunit alpha-1
  • ATP synthase subunit alpha, mitochondrial precursor
  • B-Raf proto-oncogene serine/threonine-protein kinase (p94)
  • Bcl2 antagonist of cell death
  • Bcl2-like 1
  • Calcium/calmodulin-dependent protein kinase type II alpha chain
  • Calcium/calmodulin-dependent protein kinase type IV
  • caspase 12
  • caspase 7 isoform delta
  • caspase 8 isoform G precursor
  • caspase 9 isoform alpha preproprotein
  • caspase 9 isoform beta preproprotein
  • catenin (cadherin-associated protein), beta 1, 88kDa
  • Catenin beta-1
  • Cathepsin L1 precursor
  • CD89
  • Cell division cycle protein 20 homolog
  • coagulation factor II (thrombin) receptor-like 1 precursor
  • connexin-32
  • cortactin isoform a
  • crystallin, beta B1
  • crystallin, beta B3
  • cyclin D1
  • cyclin-dependent kinase 5, regulatory subunit 2
  • development and differentiation enhancing
  • Diablo homolog, mitochondrial precursor
  • doublecortin-like kinase 1 isoform 1
  • doublecortin-like kinase 1 isoform 2
  • doublecortin-like kinase 1 isoform 3
  • doublecortin-like kinase 1 isoform 4
  • Dynactin subunit 1
  • Dynactin subunit 2
  • Dynamin-1
  • E3 ubiquitin-protein ligase CBL
  • enolase 1
  • epidermal growth factor receptor isoform a
  • FBJ osteosarcoma oncogene
  • Filamin A
  • GABA-B receptor 2
  • gap junction membrane channel protein beta 1
  • gap junction protein, alpha 8, 50kDa
  • glutathione S-transferase, pi 1
  • glycine transporter variant 1a
  • glycine transporter variant 1b
  • glycogen synthase kinase 3 alpha
  • glycogen synthase kinase 3 beta
  • Golli-mbp isoform 1
  • Golli-mbp isoform 2
  • heat shock 70kDa protein 8 isoform 1
  • huntingtin
  • Integrin alpha-3 precursor
  • integrin, beta 2 precursor
  • interleukin 2 receptor, gamma precursor
  • interleukin enhancer binding factor 3 isoform a
  • interleukin enhancer binding factor 3 isoform b
  • interleukin enhancer binding factor 3 isoform c
  • major intrinsic protein of lens fiber
  • Metabotropic glutamate receptor 1 precursor
  • microtubule-associated protein 1A
  • microtubule-associated protein 1b
  • microtubule-associated protein 2
  • microtubule-associated protein tau isoform 1
  • microtubule-associated protein tau isoform 2
  • microtubule-associated protein tau isoform 3
  • microtubule-associated protein tau isoform 4
  • microtubule-associated protein tau isoform 5
  • microtubule-associated protein tau isoform 6
  • Myc box-dependent-interacting protein 1, amphiphysin 2
  • myelin basic protein isoform 1
  • myelin basic protein isoform 2
  • myelin basic protein isoform 3
  • myelin basic protein isoform 4
  • Myocyte-specific enhancer factor 2D
  • myosin VA
  • neurofibromin 2 isoform 1
  • neurofibromin 2 isoform 2
  • neurofibromin 2 isoform 5
  • neurofibromin 2 isoform 6
  • neurofibromin 2 isoform 7
  • Neurolysin, mitochondrial precursor
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • nuclear mitotic apparatus protein 1
  • parathyroid hormone receptor 1 precursor
  • phosphoinositide-specific phospholipase C beta 1
  • Plasma membrane calcium-transporting ATPase 2
  • PREDICTED: similar to Beta crystallin A3
  • Profilin-1
  • Protamine-Z
  • Protein kinase C alpha type (PKC-alpha)
  • Protein kinase C beta type (PKC-beta)
  • Protein kinase C epsilon type (nPKC-epsilon)
  • Protein kinase C gamma type (PKC-gamma)
  • protein kinase C, alpha
  • protein kinase C, beta
  • protein kinase C, gamma
  • Protein phosphatase 1 regulatory subunit 12A
  • protein phosphatase 3, catalytic subunit, alpha isoform
  • PTK2 protein tyrosine kinase 2 isoform a
  • PTK2 protein tyrosine kinase 2 isoform b
  • Rabphilin-3A (Exophilin-1)
  • Rho GTPase-activating protein 5
  • Ryanodine receptor 1
  • S-antigen
  • Serine/threonine-protein kinase Nek2
  • SH2 domain containing 3A
  • signal transducer and activator of transcription 6
  • similar to titin isoform N2-A
  • similar to titin isoform N2-B
  • Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1)
  • Striatin
  • Synapsin-2
  • Synaptojanin-1
  • Synaptosomal-associated protein 25
  • Synaptotagmin-1
  • Syntaxin binding protein Munc18-3
  • talin 1
  • talin 2
  • tensin
  • Transcription elongation factor A protein 1
  • tubulin, beta
  • utrophin
  • v-jun sarcoma virus 17 oncogene homolog
  • Vesicle-fusing ATPase (N-ethylmaleimide-sensitive fusion protein)
  • vimentin
  • WAS protein family, member 2
  • WAS protein family, member 3
  • Wiskott-Aldrich syndrome protein family member 1
  • YY1 transcription factor
• Substrate Specificity -- Under development
• Inhibitors -- Under development
• Pathways -- Under development