ProteaseDB: MMP24

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The PMAP website is a resource for the entire scientific community to foster understanding of proteolytic pathways, and to reason about proteolysis. By bringing together information of seemingly unrelated or physically disconnected information from five databases (ProteaseDB, SubstrateDB, CutDB, ProfileDB and PathwayDB) we work to bring this new and unique tool to researchers of proteolysis, cell biologists and medical professionals.

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MMP24

Functional Attributes in Pathways

Substrates : 4 entries in CutDB for M10.023 Ext
Substrate Specificity for MMP24
Inhibitors -- Under development
Pathways -- Under development

Recent News and Literature

Immunoscreening of a cutaneous...Cancer Immunol Immunother. 2007 Jun;56(6):783-95. Epub 2006 Nov 7.
Threonine 98, the pivotal...J Biol Chem 2004 Apr 23;279(17): p17562-9
Direct activation of pro-matrix...Cancer Res 2003 Oct 15;63(20): p6758-62
Endothelial tubulogenesis within fibrin...J Cell Sci 2002 Sep 1;115(Pt 17): p3427-38
Identification and characterization of human...Cancer Res 1999 Jun 1;59(11): p2570-6

Structural Features

Structure has not yet been determined for this protein.

Click here to view a 3D model

[-] Domain Structure

MPRSRGGRAAPGPPPPPPPPGQAPRWSRWRVPGRLLLLLLPALCCLPGAARAAAAAAGAGNRAAVAVAVARADEAEAPFA

GQNWLKSYGYLLPYDSRASALHSAKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHLSRRRRNKRYALTG

QKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDRKEADIMIFFASGFHGDSSPFDGEGG

FLAHAYFPGPGIGGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHALGLEHSSDPSAIMAPFYQYMETHNFKLPQDDLQ

GIQKIYGPPAEPLEPTRPLPTLPVRRIHSPSERKHERQPRPPRPPLGDRPSTPGTKPNICDGNFNTVALFRGEMFVFKDR

WFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGELGSCLPREGIDTAL

RWEPVGKTYFFKGERYWRYSEERRATDPGYPKPITVWKGIPQAPQGAFISKEGYYTYFYKGRDYWKFDNQKLSVEPGYPR

NILRDWMGCNQKEVERRKERRLPQDDVDIMVTINDVPGSVNAVAVVIPCILSLCILVLVYTIFQFKNKTGPQPVTYYKRP

VQEWV

Cross annotation in other databases

MMP24 in: