MMP25
Functional Attributes in Pathways
-
Substrates : 52 entries in CutDB for M10.024
Ext
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Golli-mbp isoform 1
-
Golli-mbp isoform 2
-
Matrix metalloproteinase 2 preproprotein
-
myelin basic protein isoform 1
-
myelin basic protein isoform 2
-
myelin basic protein isoform 3
-
myelin basic protein isoform 4
-
Plasminogen activator, urokinase receptor isoform 1 precursor
-
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
-
Substrate Specificity for MMP25
-
Inhibitors -- Under development
-
Pathways -- Under development
Recent News and Literature
- Identification and role of the homodimerization...J Biol Chem. 2008 Oct 20.
- MT4-(MMP17) and MT6-MMP (MMP25),...Cancer Metastasis Rev. 2008 Feb 20;.
- MMP25 (MT6-MMP) is highly...J Biol Chem. 2007 Jul 27;282(30):21998-2010. Epub 2007 May 18.
- Complete restoration of cell...J Biol Chem. 2007 Mar 2;282(9):6438-43. Epub 2006 Dec 11.
- The hemopexin domain of membrane-type...J Biol Chem 2004 Dec 3;279(49): p51148-55
- Direct activation of pro-matrix...Cancer Res 2003 Oct 15;63(20): p6758-62
- Human MT6-matrix metalloproteinase: identification,...Cancer Res 2000 Feb 15;60(4): p877-82
Structural Features
MRLRLRLLALLLLLLAPPARAPKPSAQDVSLGVDWLTRYGYLPPPHPAQAQLQSPEKLRDAIKVMQRFAGLPETGRMDPG
TVATMRKPRCSLPDVLGVAGLVRRRRRYALSGSVWKKRTLTWRVRSFPQSSQLSQETVRVLMSYALMAWGMESGLTFHEV
DSPQGQEPDILIDFARAFHQDSYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFGSKDGEGTDLFAVAVHEFGHALG
LGHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQLYGKAPQTPYDKPTRKPLAPPPQPPASPTHSPSFPIPDRCEGN
FDAIANIRGETFFFKGPWFWRLQPSGQLVSPRPARLHRFWEGLPAQVRVVQAAYARHRDGRILLFSGPQFWVFQDRQLEG
GARPLTELGLPPGEEVDAVFSWPQNGKTYLVRGRQYWRYDEAAARPDPGYPRDLSLWEGAPPSPDDVTVSNAGDTYFFKG
AHYWRFPKNSIKTEPDAPQPMGPNWLDCPAPSSGPRAPRPPKATPVSETCDCQCELNQAAGRWPAPIPLLLLPLLVGGVA
SR
Cross annotation in other databases
MMP25 in:
Gene Cards
- Diseases
- Expression
- SNP
- Drugs
Other Links
- Human Protein Atlas
- iHOP
- GNF Sym Atlas
- NCBI Homologs
- OMIM
- MEROPS
Functional Attributes in Pathways
-
Substrates : 52 entries in CutDB for M10.024
Ext
- Golli-mbp isoform 1
- Golli-mbp isoform 2
- Matrix metalloproteinase 2 preproprotein
- myelin basic protein isoform 1
- myelin basic protein isoform 2
- myelin basic protein isoform 3
- myelin basic protein isoform 4
- Plasminogen activator, urokinase receptor isoform 1 precursor
- serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
- Substrate Specificity for MMP25
- Inhibitors -- Under development
- Pathways -- Under development
Recent News and Literature
- Identification and role of the homodimerization...J Biol Chem. 2008 Oct 20.
- MT4-(MMP17) and MT6-MMP (MMP25),...Cancer Metastasis Rev. 2008 Feb 20;.
- MMP25 (MT6-MMP) is highly...J Biol Chem. 2007 Jul 27;282(30):21998-2010. Epub 2007 May 18.
- Complete restoration of cell...J Biol Chem. 2007 Mar 2;282(9):6438-43. Epub 2006 Dec 11.
- The hemopexin domain of membrane-type...J Biol Chem 2004 Dec 3;279(49): p51148-55
- Direct activation of pro-matrix...Cancer Res 2003 Oct 15;63(20): p6758-62
- Human MT6-matrix metalloproteinase: identification,...Cancer Res 2000 Feb 15;60(4): p877-82
Structural Features
MRLRLRLLALLLLLLAPPARAPKPSAQDVSLGVDWLTRYGYLPPPHPAQAQLQSPEKLRDAIKVMQRFAGLPETGRMDPG
TVATMRKPRCSLPDVLGVAGLVRRRRRYALSGSVWKKRTLTWRVRSFPQSSQLSQETVRVLMSYALMAWGMESGLTFHEV
DSPQGQEPDILIDFARAFHQDSYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFGSKDGEGTDLFAVAVHEFGHALG
LGHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQLYGKAPQTPYDKPTRKPLAPPPQPPASPTHSPSFPIPDRCEGN
FDAIANIRGETFFFKGPWFWRLQPSGQLVSPRPARLHRFWEGLPAQVRVVQAAYARHRDGRILLFSGPQFWVFQDRQLEG
GARPLTELGLPPGEEVDAVFSWPQNGKTYLVRGRQYWRYDEAAARPDPGYPRDLSLWEGAPPSPDDVTVSNAGDTYFFKG
AHYWRFPKNSIKTEPDAPQPMGPNWLDCPAPSSGPRAPRPPKATPVSETCDCQCELNQAAGRWPAPIPLLLLPLLVGGVA
SR
Cross annotation in other databases
MMP25 in:
- Gene Cards
- Diseases
- Expression
- SNP
- Drugs
- Other Links
- Human Protein Atlas
- iHOP
- GNF Sym Atlas
- NCBI Homologs
- OMIM
- MEROPS

