PMAP: The Proteolysis Map

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CutDB

PathwayDB

ProteaseDB

SubstrateDB

ProfileDB
Toolkit
About

Mission
The PMAP website is a resource for the entire scientific community to foster understanding of proteolytic pathways, and to reason about proteolysis. By bringing together information of seemingly unrelated or physically disconnected information from five databases (ProteaseDB, SubstrateDB, CutDB, ProfileDB and PathwayDB) we work to bring this new and unique tool to researchers of proteolysis, cell biologists and medical professionals.

The Team

Usage Stats

Use PMAP Services
Presentations

Creating a web link to PMAP Databases:

1. Search for cleavage events by protease description:

http://cutdb.burnham.org/relation/pmap2cutdb?protease_definition=

Example:

http://cutdb.burnham.org/relation/pmap2cutdb?protease_definition=caspase-6

2. Search for cleavage events by protease organism:

http://cutdb.burnham.org/relation/pmap2cutdb?protease_organism=

Example:

http://cutdb.burnham.org/relation/pmap2cutdb?protease_organism=Mus musculus

3. Search for cleavage events by substrate NCBI accession number:

http://cutdb.burnham.org/relation/pmap2cutdb?substrate_accession=

Example:

http://cutdb.burnham.org/relation/pmap2cutdb?substrate_accession=NP_006844

4. Search for cleavage events by substrate organism:

http://cutdb.burnham.org/relation/pmap2cutdb?substrate_organism=

Example:

http://cutdb.burnham.org/relation/pmap2cutdb?substrate_organism=Mus musculus

5. Search for cleavage events by disease:

http://cutdb.burnham.org/relation/pmap2cutdb?disease=

Example:

http://cutdb.burnham.org/relation/pmap2cutdb?disease=AIDS

6. Search for cleavage events by substrate UniProt ID:

http://cutdb.burnham.org/relation/pmap2cutdb?substrate_UniProt=

Example:

http://cutdb.burnham.org/relation/pmap2cutdb?substrate_UniProt=HGF_HUMAN