| Structure Region |
Pdb Id |
Title |
Resolution |
Technique |
|
1DAN
| complex of active site inhibited human blood coagulation factor viia with human recombinant soluble tissue factor |
2 |
x-ray |
|
1QFK
| structure of human factor viia and its implications for the triggering of blood coagulation |
2.8 |
x-ray |
|
1DVA
| crystal structure of the complex between the peptide exosite inhibitor e-76 and coagulation factor viia |
3 |
x-ray |
|
1FAK
| human tissue factor complexed with coagulation factor viia inhibited with a bpti-mutant |
2.1 |
x-ray |
|
1JBU
| coagulation factor vii zymogen (egf2/protease) in complex with inhibitory exosite peptide a-183 |
2 |
x-ray |
|
1CVW
| crystal structure of active site-inhibited human coagulation factor viia (des-gla) |
2.28 |
x-ray |
|
1KLI
| cofactor-and substrate-assisted activation of factor viia |
1.69 |
x-ray |
|
1KLJ
| crystal structure of uninhibited factor viia |
2.44 |
x-ray |
|
1J9C
| crystal structure of tissue factor-factor viia complex |
2.9 |
x-ray |
|
1W0Y
| tf7a_3771 complex |
2.5 |
x-ray |
|
1O5D
| dissecting and designing inhibitor selectivity determinants at the s1 site using an artificial ala190 protease (ala190 upa) |
2.05 |
x-ray |
|
1W2K
| tf7a_4380 complex |
3 |
x-ray |
|
1Z6J
| crystal structure of a ternary complex of factor viia/tissue factor/pyrazinone inhibitor |
2 |
x-ray |
|
1WQV
| human factor viia-tissue factor complexed with propylsulfonamide-d-thr-met-p-aminobenzamidine |
2.5 |
x-ray |
|
1W7X
| factor7 - 413 complex |
1.8 |
x-ray |
|
1W8B
| factor7 - 413 complex |
3 |
x-ray |
|
1YGC
| short factor viia with a small molecule inhibitor |
2 |
x-ray |
|
1WTG
| human factor viia-tissue factor complexed with ethylsulfonamide-d-biphenylalanine-gln-p-aminobenzamidine |
2.2 |
x-ray |
|
1WUN
| human factor viia-tissue factor complexed with ethylsulfonamide-d-trp-gln-p-aminobenzamidine |
2.4 |
x-ray |
|
1WV7
| human factor viia-tissue factor complexed with ethylsulfonamide-d-5-propoxy-trp-gln-p-aminobenzamidine |
2.7 |
x-ray |
|
1WSS
| human factor viia-tissue factor in complex with peprid mimetic inhibitor that has two charge groups in p2 and p4 |
2.6 |
x-ray |
|
2B7D
| factor viia inhibitors: chemical optimization, preclinical pharmacokinetics, pharmacodynamics, and efficacy in a baboon thrombosis model |
2.24 |
x-ray |
|
2F9B
| discovery of novel heterocyclic factor viia inhibitors |
2.54 |
x-ray |
|
2FLB
| discovery of a novel hydroxy pyrazole based factor ixa inhibitor |
1.95 |
x-ray |
|
2BZ6
| orally available factor7a inhibitor |
1.6 |
x-ray |