u-plasminogen activator

Structure 1C5X


Structures

Structure Region Pdb Id Title Resolution Technique
1SC8 urokinase plasminogen activator b-chain-j435 complex 2.4 x-ray
1VJ9 urokinase plasminogen activator b-chain-jt464 complex 2.4 x-ray
1VJA urokinase plasminogen activator b-chain-jt464 complex 2 x-ray
1LMW lmw u-pa structure complexed with egrcmk (glu-gly-arg chloromethyl ketone) 2.5 x-ray
1GJ7 engineering inhibitors highly selective for the s1 sites of ser190 trypsin-like serine protease drug targets 1.5 x-ray
1GJ8 engineering inhibitors highly selective for the s1 sites of ser190 trypsin-like serine protease drug targets 1.64 x-ray
1GJA engineering inhibitors highly selective for the s1 sites of ser190 trypsin-like serine protease drug targets 1.56 x-ray
1GJB engineering inhibitors highly selective for the s1 sites of ser190 trypsin-like serine protease drug targets 1.9 x-ray
1O3P elaborate manifold of short hydrogen bond arrays mediating binding of active site-directed serine protease inhibitors 1.81 x-ray
1O5A dissecting and designing inhibitor selectivity determinants at the s1 site using an artificial ala190 protease (ala190 upa) 1.68 x-ray
1O5B dissecting and designing inhibitor selectivity determinants at the s1 site using an artificial ala190 protease (ala190 upa) 1.85 x-ray
1O5C dissecting and designing inhibitor selectivity determinants at the s1 site using an artificial ala190 protease (ala190 upa) 1.63 x-ray
1C5W structural basis for selectivity of a small molecule, s1- binding, sub-micromolar inhibitor of urokinase type plasminogen activator 1.94 x-ray
1C5X structural basis for selectivity of a small molecule, s1- binding, sub-micromolar inhibitor of urokinase type plasminogen activator 1.75 x-ray
1C5Y structural basis for selectivity of a small molecule, s1- binding, sub-micromolar inhibitor of urokinase type plasminogen activator 1.65 x-ray
1C5Z structural basis for selectivity of a small molecule, s1- binding, sub-micromolar inhibitor of urokinase type plasminogen activator 1.85 x-ray
1GJ9 engineering inhibitors highly selective for the s1 sites of ser190 trypsin-like serine protease drug targets 1.8 x-ray
1GJC engineering inhibitors highly selective for the s1 sites of ser190 trypsin-like serine protease drug targets 1.73 x-ray
1GJD engineering inhibitors highly selective for the s1 sites of ser190 trypsin-like serine protease drug targets 1.75 x-ray
1EJN urokinase plasminogen activator b-chain inhibitor complex 1.8 x-ray
1F5K urokinase plasminogen activator b-chain-benzamidine complex 1.8 x-ray
1F5L urokinase plasminogen activator b-chain-amiloride complex 2.1 x-ray
1F92 urokinase plasminogen activator b chain-uki-1d complex 2.6 x-ray
1OWD substituted 2-naphthamidine inhibitors of urokinase 2.32 x-ray
1OWI substituted 2-naphthamidine inhibitors of urokinase 2.93 x-ray
1OWJ substituted 2-naphthamidine inhibitors of urokinase 3.1 x-ray
1OWK substituted 2-naphthamidine inhibitors of urokinase 2.8 x-ray
1SQT substituted 2-naphthamidine inhibitors of urokinase 1.9 x-ray
1U6Q substituted 2-naphthamadine inhibitors of urokinase 2.02 x-ray
1OWE substituted 2-naphthamidine inhibitors of urokinase 1.6 x-ray
1OWH substituted 2-naphthamidine inhibitors of urokinase 1.61 x-ray
1SQA substituted 2-naphthamidine inhibitors of urokinase 2 x-ray
1SQO substituted 2-naphthamidine inhibitors of urokinase 1.84 x-ray
1GI8 a novel serine protease inhibition motif involving a multi- centered short hydrogen bonding network at the active site 1.75 x-ray
1FV9 crystal structure of human microurokinase in complex with 2- amino-5-hydroxy-benzimidazole 3 x-ray
1GI7 a novel serine protease inhibition motif involving a multi- centered short hydrogen bonding network at the active site 1.79 x-ray
1GI9 a novel serine protease inhibition motif involving a multi- centered short hydrogen bonding network at the active site 1.8 x-ray
1URK nmr
2FD6 structure of human urokinase plasminogen activator in complex with urokinase receptor and an anti-upar antibody at 1.9 a 1.9 x-ray
1KDU nmr